Formulation and Characterization of Clotrimazole Micro Emulsion for Topical Drug Delivery

Abstract

An antimycotic drug like clotrimazole is used for treating Candida albicans and other fungal infections. Clotrimazole seems
to be a topical therapy treating vulvovaginal candidiasis, tineapedis, and oropharyngeal candidiasis. That is a synthetic azole
antimycotic. By decreasing the production of ergosterol, this drug inhibits fungal growth. Clotrimazole has become a
medication of interest for a variety of illnesses, including sickle cell anemia, malaria, and some cancers, in addition to its
antimycotic properties. It is mixed with other molecules to create clotrimazole compounds with enhanced pharmacological
effectiveness. Numerous novel pharmaceutical formulations enabling variable releases developed. Clotrimazole is a welltolerated,
little-adverse drug. However, certain immunocompromised individuals are developing treatment resistance. In this
study, we discussed the pharmaceutical chemistry, use, and pharmacology of clotrimazole.