A Relentless and Aggressive Proliferation of a Verrucous Lesion

Abstract

Proliferative verrucous leukoplakia (PVL) was first described by Hansen in 1985, is a clinical form of oral leukoplakia defined by its progressive features, and potential to develop into cancer. PVL behaves in a more aggressive and relentless manner than the more innocuous white oral lesions that it can resemble clinically. In this paper, we report a case of PVL transforming into squamous cell carcinoma.