Devic’s disease – A case report
Keywords:
Demyelinating disorder, Devic disease, Multiple sclerosis, Neuromyelitis optica, Optic neuritis, Transverse myelitisAbstract
Devic disease (Neuromyelitis Optica – [NMO]) is a severe inflammatory demyelinating condition that targets astrocytes in the optic nerves and spinal cord. It is characterized by optic neuritis and transverse myelitis. The disease is very rare with an incidence of 0.05–0.4% and female predominance. NMO is easily misdiagnosed with multiple sclerosis (MS) as characterized by relapses. The best predictor to differentiate NMO from MS is the presence of serum antibody to Aquaporin-4 called as NMO-immunoglobulin G.
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