Predictive value of umbilical cord blood albumin levels as an indicator of neonatal jaundice in healthy term newborns

Authors

  • Prerna Bhat
  • S.R. Agarkhedkar
  • Shradha Salunke

DOI:

https://doi.org/10.32677/IJCH.2020.v07.i02.001

Keywords:

Cord serum albumin, Jaundice, Neonatal hyperbilirubinemia, Prediction

Abstract

Background: Neonatal hyperbilirubinemia (NH) is the most common cause of readmission during the early neonatal period. There is a need to find the methods of screening babies at higher risk of developing jaundice before discharge. Objectives: The objectives of this study were to find out the predictive value of cord serum albumin (CSA) levels as an indicator of neonatal jaundice. Materials and Methods: A cross-sectional study conducted at a tertiary hospital of Maharashtra, from October 2017 to September 2019 on 410 term newborns. CSA was collected at birth and correlated with serum bilirubin levels collected at 48 h of life. Statistical analysis was performed and the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) with a 95% confidence interval obtained. Results: Of 410 cases, 266 (64.8%) developed clinical jaundice, of which 148 (93.6%) had albumin levels <2.8 g/dl, 79 (74.5%) between 2.8 and 3.3 g/dl, and 39 (26.7%) >3.3 g/dl. At CSA level <2.8 g/dl, the sensitivity of 93.67% with PPV and NPV of 51.57% and 94.65%, respectively, was found. At CSA level 2.8–3.3 g/dl, the sensitivity estimated was 85.98% with a PPV and NPV of 85.34% and 74.31%, respectively. Conclusion: In this study, CSA appears to be a risk indicator in predicting neonatal hyperbilirubinemia. CSA level <2.8 g/dl is a high-risk factor for the future development of neonatal hyperbilirubinemia, while those with CSA level >3.3 g/dl are probably safe for early discharge from the hospital.

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Published

2020-02-25

Issue

Section

Original Articles

How to Cite

Predictive value of umbilical cord blood albumin levels as an indicator of neonatal jaundice in healthy term newborns. (2020). Indian Journal of Child Health, 7(2), 47-49. https://doi.org/10.32677/IJCH.2020.v07.i02.001

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