Unusual presentation of JAK2-negative polycythemia

Authors

  • Akesh Thomas
  • Alex Robert
  • Don Babu Chemplavil

Keywords:

Erythrocytosis, JAK2-negative polycythemia, Polycythemia vera, Secondary hypertension

Abstract

Polycythemia vera is a relatively rare disease occurring in 0.02–2.8 per million population. Globally, about 95% of PV is due
to JAK2V617F mutation in the chromosome 9p. The remaining 5% were found to have a wide range of mutations including
JAK2 exon12 mutation and calreticulin (CALR) mutation. In India, the incidence of JAK2-negative polycythemia is relatively
high, reaching up to 18%. Polycythemia usually presents as symptoms secondary to hyperviscosity or as symptoms secondary to
increased histamine release by the cells. Herein, we describe a 46-year-old Indian male presented with a headache and found to be
in hypertensive urgency, which was later found to be secondary to JAK2-negative polycythemia.

Downloads

Download data is not yet available.

Downloads

Published

2018-06-25

Issue

Section

Case Report

How to Cite

Unusual presentation of JAK2-negative polycythemia. (2018). Indian Journal of Case Reports, 4(3), 176-178. https://mansapublishers.com/index.php/ijcr/article/view/973

Most read articles by the same author(s)

<< < 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 > >>