Skin mediated human papillomavirus infection in breast: A report of four cases

Authors

  • Saimul Islam
  • Hemantika Dasgupta
  • Mukta Basu
  • Anup Roy
  • Neyaz Alam
  • Gautam Kumar Mandal
  • Susanta Roychoudhury
  • Chinmay Kumar Panda

Keywords:

Breast cancer, breast skin, E6/E7 oncoproteins, human papillomavirus, human papillomavirus transmission

Abstract

To address the ambiguity of different modes of human papillomavirus (HPV) transmission in breast, the immunohistochemical expression of two oncoproteins E6/E7 of HPV16 was analyzed in primary breast cancer (BC) and adjacent normal skin of 4 samples. The patients were of 35–55 years old having no previous history of cancer. The E6/E7 expressions were evident in both skin and BC. In skin, high/moderate cytoplasmic expressions of E6/E7 proteins were seen in all samples, whereas in BC, high/moderate cytoplasmic expressions of the proteins were observed in 2–3 samples. Thus, it seems that HPV infection in the breast may occur through the skin.

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Published

2018-03-20

Issue

Section

Case Report

How to Cite

Skin mediated human papillomavirus infection in breast: A report of four cases. (2018). Indian Journal of Case Reports, 4(2), 98-102. https://mansapublishers.com/index.php/ijcr/article/view/792

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