Salmonella typhimurium meningitis in an immunocompetent infant

Abstract

Meningitis due to Salmonella is rare and associated with high morbidity, mortality, and relapse rates despite adequate treatment. Here, we report a case of meningitis due to Salmonella typhimurium in an immunocompetent infant. The child was brought to the
pediatric emergency department with complaints of high-grade fever, loose motions, vomiting, and irritability of 3-day duration. Cerebrospinal fluid (CSF) analysis was suggestive of acute bacterial meningitis, and the child was started on intravenous ceftriaxone.
The CSF and blood cultures grew S. typhimurium and the treatment was accordingly modified. His serum immunoglobulin levels were normal, and enzyme-linked immunosorbent assay for HIV was negative. Clinical course, antibiotic treatment, and outcome of the case are discussed here.