Steroid-responsive dual neuronal antibody-positive paraneoplastic encephalitis
DOI:
https://doi.org/10.32677/ijcr.v10i3.4175Keywords:
Anti-Yo and Anti-Zic-4, Paraneoplastic encephalitisAbstract
Here, we report the case of an elderly African male with multifocal neuraxial involvement in the form of progressive parkinsonism and ataxia over a year. On evaluation, dual neuronal antibody positivity was detected. A diagnosis of paraneoplastic encephalitis was made without any detection of primary neoplasm. He was successfully managed with pulse steroid therapy followed by oral steroid and steroid-sparing oral immunosuppressive drug without any need for intravenous immunoglobulin or plasma exchange.
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Copyright (c) 2024 Nemalidinne Krishna Vani, Rajiv Anand, Varun Rehani
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