Hyperimmunoglobulin E syndrome and multiple brain abscesses

Abstract

Hyperimmunoglobulin E (HyperIgE) syndrome is a rare primary immunodeficiency disease characterized
by recurrent skin and pulmonary infections and an elevated serum IgE level. We report a female neonate
with hyperIgE syndrome who presented with multiple brain abscesses and superficial cold abscesses caused
by Staphylococcus aureus and also developed pneumonia later on. On follow-up, she developed pneumonia
twice and cold abscess once. She responded well to conservative management.