Neonatal lupus erythematous – A report of three cases

Authors

  • Punit S Chhajed
  • S V Savaskar
  • N S Bhori
  • S T Bandichhode

DOI:

https://doi.org/10.32677/IJCH.2017.v04.i04.040

Keywords:

Autoimmune, Congenital heart block, Neonatal lupus, Raccoon eyes, SLE

Abstract

Neonatal lupus erythematosus (NLE) is a rare acquired autoimmune disorder clinically characterized by skin lesions that resemble those of subacute or discoid lupus erythematosus and/or congenital heart bock. Skin and cardiac manifestations coexist only in 10% of the patients. It is caused by transplacental passage of maternal autoantibodies, usually anti-Ro/SS-A and /or anti-La/SS-B and less commonly anti-U1 ribonucleoprotein. Mothers of the infants with NLE are either asymptomatic or diagnosed with autoimmune disease. We describe 3 neonates with clinical and immunological findings compatible with NLE, their progress and outcome.

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Published

2017-12-25

How to Cite

Neonatal lupus erythematous – A report of three cases. (2017). Indian Journal of Child Health, 4(4), 631-634. https://doi.org/10.32677/IJCH.2017.v04.i04.040