Granulomatous prostatitis with raised prostate-specific antigen levels; mimicker of malignancy

Abstract

Granulomatous prostatitis is a rare and distinctive form of prostatitis that can be misdiagnosed clinically as carcinoma,radiologically by ultrasound, and histopathologically. It is quite uncommon in needle biopsy cases, with an incidence of<1%. Furthermore, it is a rare localized inflammatory condition of the prostate that forms a localized lesion/nodule andis associated with raised prostate-specific antigen levels. Almost exclusively diagnosed by histological examination.Classification includes non-specific granulomatous prostatitis, infectious granulomas, post-surgical granulomas,systemic granulomatous prostatitis, xanthogranulomatous prostatitis, and malakoplakia prostatitis.