Eastern Journal of Medical Sciences https://mansapublishers.com/EJMS <pre><strong>ISSN: e-ISSN</strong> - 2456- 2785<br /><strong>Discipline:</strong> All Medical, Surgical and Dental Specialities<br /><strong>Starting Year:</strong> 2016<br /><strong>Current volume:</strong> Volume 5 <br /><strong>Issue per year:</strong> 4 issues<br /><strong>Editor-in-chief:</strong> Dr. Sayan Bhattacharyya, India<br /><strong>Indexing:</strong> Index Copernicus, Journal Guide, Research Bible, World Cat, Sherpa Romeo, Google Scholar<br /><strong>E-mail: <a href="mailto:editor.ijpds@mansapublishers.com" target="_blank" rel="noopener">editor.ejms@mansapublishers.com</a> </strong></pre> Mansa STM Publishers en-US Eastern Journal of Medical Sciences 2456-2785 An unusual presentation of human immunodeficiency virus and dengue coinfection https://mansapublishers.com/EJMS/article/view/2568 <p>The global incidence of dengue has grown dramatically in recent decades, with around half of the world’s population currently at risk. Despite an overlapping epidemiology, limited data are available on human immunodeficiency virus (HIV) and dengue coinfection. Some reported evidence suggests that the patients with HIV infection are more at risk of a severe dengue outcome, while other reports suggest a transitory inhibition of the HIV-1 viral load, as well as a benign clinical progression of dengue. Our case is of a 44-year-old HIV-infected obese gentleman with typical features of dengue infection. He was closely monitored and his clinical profile was thoroughly studied during in-hospital stay and post-discharge. However, further research is required to comprehend the pathology, as well as the clinical course of these coinfections.</p> Meghna Dutta Suddhasatwya Chatterjee Copyright (c) 2020 Meghna Dutta, Suddhasatwya Chatterjee http://creativecommons.org/licenses/by-nc-nd/4.0 2021-01-12 2021-01-12 88 90 Primary malignant melanoma of small intestine – A rare case report https://mansapublishers.com/EJMS/article/view/2658 <p>Primary malignant melanoma of the intestine is an extremely rare lesion that may arise from large bowel. Hereby, we report a case of a 35-year-old female who presented with abdominal pain of 1 month duration. On positron emission tomography-computed tomography, a hypermetabolic mass observed in the pelvic ileal loop with no lesions elsewhere in the body. The surgically excised specimen was diagnosed as primary small intestinal melanoma by histopathological examination, which was further confirmed by the presence of melanoma markers, that is, Melan-A, HMB45, and S100 protein.</p> Palak Patel Prashant Parikh Bhavna Mehta Rutvik Raval Rahul Yadav Sandip Shah Mandava Rao Copyright (c) 2020 http://creativecommons.org/licenses/by-nc-nd/4.0 2021-01-12 2021-01-12 91 92 Surgical depigmentation of gingiva using scalpel https://mansapublishers.com/EJMS/article/view/2663 <p>Smile and esthetics play a major role in improving a person’s physical appearance and also moral courage. Good alignment of teeth and proper exposure of gingiva are the fundamental factors influencing the smile and esthetics of a person. Overexposure of gingiva and excessive pigmentation of gingiva affect the smile and esthetics of a person deliberately. Excessive pigmentation of gingiva can be due to various reasons such as smoking, hormonal, racial, and underlying systemic disorders. Depigmentation techniques are commonly used in the management of patients with excessive melanin pigmentation due to racial reasons. Hereby, we report a case of surgical depigmentation of the upper anterior gingiva using a scalpel in a normal healthy patient with excessive melanin pigmentation.</p> Maria Subash Aaron Muthuraj Arun Maradi Fazal Ilahi Jamesha Nimisha Gopal Copyright (c) 2020 http://creativecommons.org/licenses/by-nc-nd/4.0 2021-01-12 2021-01-12 93 95 Experience with the use of handheld Doppler for fetal heart rate monitoring during coronavirus disease-19 pandemic https://mansapublishers.com/EJMS/article/view/2571 <p><strong>Background:</strong> Fetal heart rate (FHR) monitoring during intrapartum care is important; however, the use of Doppler during coronavirus disease (COVID-19) pandemic needs to be investigated especially in light of the enhanced infection prevention (IP) required during labor and childbirth. The present study was carried out to evaluate the experience of using a handheld Doppler having both continuous and intermittent monitoring features in seven health facilities across three states. <strong>Materials and</strong> <strong>Methods: </strong>Program data including case load, frequency of monitoring, and fetal outcome was obtained from January to March 2020 were compared with data during the lockdown period from April to June 2020. A semi-structured questionnaire was used for a telephonic qualitative interview of eight service providers from the seven facilities to supplement the quantitative data. Transcripts were analyzed using ATLAS.ti to find out how the Doppler was being used. <strong>Results:</strong> There was decrease in the case load during lockdown; however, there was no decrease in the frequency of monitoring. There was no difference on rate of abnormal FHR detected, stillbirths, and asphyxia. IP protocol was followed in all facilities. The handheld Doppler was used by four facilities to continuously monitor pregnant women. While, study participants reported that strapping the belt for continuous monitoring reduced exposure to suspected COVID cases, two participants believed that strapping could be a risk factor for transmission. <strong>Conclusion:</strong> Usage of the Doppler for FHR detection can be used for monitoring progress during labor using IP protocol.</p> Devina Bajpayee Ritu Agrawal Sourav Ghosh Dastidar Nitin Bisht Ranjan Kumar Panda Arvind Kumar Enisha Sarin Harish Kumar Copyright (c) 2020 http://creativecommons.org/licenses/by-nc-nd/4.0 2021-01-12 2021-01-12 74 78 Evaluation of errors during different phases of coronavirus disease 2019 TrueNat testing in a tertiary care hospital https://mansapublishers.com/EJMS/article/view/2627 <p>Background: Although diagnostic errors have always significantly attributed to clinical and economical losses, now in the ongoing coronavirus disease 2019 (COVID-19) pandemic, the impact of these errors has unquestionably increased multifold. In the present scenario, reporting of false-negative or false-positive test results may adversely affect the public health measures and government restrictive policies, established for the containment of COVID-19 in addition to enhancing the individual suffering and economic burden. The only way to reduce errors in various phases of COVID-19 testing is to evaluate them thoroughly and subsequently follow them up with effective corrective actions. Materials and Methods: The present study was conducted at a tertiary care center, approved by Indian Council of Medical Research for COVID-19 TrueNat testing. Information regarding errors and subsequent corrective actions in preanalytical, analytical, and post-analytical phases of TrueNat testing for COVID-19 were collected. Results: A total of 112 testing errors were observed in the TrueNat testing of 1108 samples during the study duration. Around 58.93% errors occurred in the preanalytical phase of TrueNat testing, followed by 39.29% and 1.79% errors in the analytical phase and post-analytical phases, respectively. Poor quality samples constituted the predominant cause of error in the preanalytical phase. Conclusion: Delivery of accurate results is of paramount importance in this COVID-19 pandemic. A thorough analysis of the various phases of COVID-19 testing will help identify and understand the errors and implement effective corrective actions.</p> Nisha Goyal Abha Sharma Poonam Loomba B Mishra Archana Thakur Copyright (c) 2020 http://creativecommons.org/licenses/by-nc-nd/4.0 2021-01-12 2021-01-12 79 83 Histomorphological study of gastric mucosal biopsy in dyspepetic patients and its association with Helicobacter pylori infection https://mansapublishers.com/EJMS/article/view/2680 <p>Background: The rationale of the study was to evaluate the morphological changes of chronic gastritis and its association with<br>Helicobacter pylori infection and the efficacy of hematoxylin and eosin (H &amp; E) and Giemsa techniques in a limited set up which<br>helps in providing the vital data for subsequent treatment regimen. Materials and Methods: In this prospective study, 50 endoscopic<br>biopsies were obtained from dyspeptic patients from January 2016 to June 2017. The samples were fixed in 10% buffered formalin<br>and histopathological slides were prepared using paraffin blocks and subsequently stained with routine H &amp; E and special stain<br>with Giemsa. Results: There was a male preponderance in the study with a ratio of 2.3:1; the mean age of patients was 37.59 years. Of<br>the 50 patients, 47 patients (94%) had chronic gastritis. Twenty-one out of 47 samples showed positivity for H. pylori with routine<br>H &amp; E staining, which was confirmed with the modified Giemsa staining method. Conclusion: Our study highlights the association<br>of H. pylori in patients with functional dyspepsia and demonstrate the importance of cost-effective Giemsa staining which can be<br>practically applicable in Indian set-up for the detection of H. pylori.</p> Prachi M Shanthi Kasa Somsekhar Copyright (c) 2020 http://creativecommons.org/licenses/by-nc-nd/4.0 2021-01-12 2021-01-12 84 87 Close-kin marriage – An injustice to forthcoming generations https://mansapublishers.com/EJMS/article/view/2619 <p>Consanguineous marriage is the union between two individuals who are related as second cousins or closer and who have a common ancestor. There are various contributing factors to these marriages, namely, economic, cultural, social factors, and cultural isolation. Many societies nowadays do not allow marriages between close relatives, perhaps as a result of observations on the progeny of consanguineous marriages and the fear of unhealthy offsprings. This review article mainly intends to throw light on the genetic abnormalities caused by consanguineous marriages. It aspires to reveal the mystery behind the uncut diamonds sparkling as healthy children.</p> C Chrishantha Joybell M Kawin Kumar Copyright (c) 2020 http://creativecommons.org/licenses/by-nc-nd/4.0 2021-01-12 2021-01-12 70 73