Eastern Journal of Medical Sciences 2020-09-29T21:16:21+0530 Sayan Bhattacharyya Open Journal Systems <pre><strong>ISSN: e-ISSN</strong> - 2456- 2785<br /><strong>Discipline:</strong> All Medical, Surgical and Dental Specialities<br /><strong>Starting Year:</strong> 2016<br /><strong>Current volume:</strong> Volume 5 <br /><strong>Issue per year:</strong> 4 issues<br /><strong>Editor-in-chief:</strong> Dr. Sayan Bhattacharyya, India<br /><strong>Indexing:</strong> Index Copernicus, Journal Guide, Research Bible, World Cat, Sherpa Romeo, Google Scholar<br /><strong>E-mail: <a href="" target="_blank" rel="noopener"></a> </strong></pre> The emotional and psycho-social consequences of coronavirus disease-19 pandemic – A glimpse into the post-pandemic society 2020-09-29T21:16:21+0530 Smrithi Chhabra <p>The coronavirus disease (COVID-19) pandemic has swept across the globe so devastatingly causing high morbidity and mortality and has brought in its wake, not only social and economic problems but also a myriad of psychological problems which if not addressed properly may contribute considerably to a significant loss of productivity in the society. As per the saying “A sound mind in a sound body,” physical and mental health is equally important and interdependent on each other. In the present scenario, unfortunately, with people suffering from physical illnesses, as well as devastating mental sequelae of the pandemic has resulted in social, financial, economic, and emotional uncertainties. Therefore, it is most important to identify and to treat the mental health problems faced by general population, quarantined people, health-care professionals, at-risk-groups, and the victims of COVID-19 pandemic. The mental health problems can be in the form of depressive disorders, various anxiety disorders, stress related disorders, suicide and intentional self-harm, grief reaction, substance abuse (alcohol, tobacco, cannabis, and opioids), and domestic violence. Although, limited resources available to us during these difficult times, this should not dissuade us from ensuring optimal mental health and trying to keep the struggling humanities “sane” during this pandemic. These resources must be used judiciously and appropriately, with necessary modifications (telephonic/audio-video consultations and counseling) to prepare a society which can move forward in the post pandemic era.</p> 2020-09-28T00:00:00+0530 Copyright (c) 2020 Association of antinuclear antibodies with toxic epidermal necrolysis – A novel manifestation 2020-07-25T16:55:02+0530 Meghna Dutta Suddhasatwya Chatterjee Sraboni Ghosh Zoha Suresh Ramasubban <p>Toxic epidermal necrolysis (TEN) is a potentially life-threatening dermatologic disorder characterized by widespread erythema, necrosis, and bullous detachment of the epidermis of skin and mucous membranes, resulting in exfoliation and possible sepsis and/or morbidity/mortality. Exact diagnosis of lesions is very important in terms of therapeutic intervention as well as outcome. As cutaneous hypersensitivity reactions are known to occur with increased frequency in connective tissue disease, differentiating lesions of systemic lupus erythematosus that simulate drug-induced TEN is a challenge in the practical scenario. In this case series, we discuss about three patients aged between 24 and 67 years, who presented with vesiculobullous lesions all over the body and oral mucosal ulcerations. Each of them was initially admitted in the Critical Care Unit with a provisional diagnosis of TEN. Two of the three patients recovered well and were discharged. However, the third patient, who was the oldest and had multiple comorbidities, could not be saved and succumbed after 75 days of hospital stay.</p> 2020-09-08T00:00:00+0530 Copyright (c) 2020 Paraneoplastic diseases associated with non-Hodgkin’s lymphoma – Case series 2020-09-03T19:27:10+0530 Abhraneel Guha Kundan Chaurasia Bhaswati Dasgupta Nath Raja Basu Avijit Das Digbijoy Choudhury Mandeep Joshi Ajoy Krishna Sarkar <p>Non-Hodgkin’s lymphoma (NHL) is malignancies of white blood cells called lymphocytes. Although fever and weight loss are the main symptoms associated, NHL is known for its unusual presentation. Variants of NHL include diffuse large B cell, Mantle cell, Burkitt’s Lymphoma, Precursor B cell type, and among many. At times, paraneoplastic diseases often mask the underlying lymphoma and hence delaying the diagnosis. Through this case series, we discuss the association of NHL with paraneoplastic diseases. NHL was associated with dorsal myelitis in the first case, metastatic spread in abdomen in the second case and with Steven Johnson syndrome in the third case.</p> 2020-09-08T00:00:00+0530 Copyright (c) 2020 Malaria: Prevalence and related factors in children at Aba, Southeast Nigeria 2020-07-31T17:18:19+0530 Chukwuemeka Ngozi Onyearugha Nneka Chioma Okoronkwo Prince Ezenwa Onyemachi <p><strong>Background:</strong> Childhood malaria has remained a major public health burden. It severely affects children aged under-5 years, particularly in Sub-Saharan Africa. Curbing the prevalence of malaria begins with determining the prevalence and related factors of the disease in the community. <strong>Objective:</strong> The objective of the study was to determine the prevalence and related factors of malaria in children at Aba, Southeast Nigeria. Materials and Methods: In this retrospective study, 275 case files of children admitted with malaria in the Department of Paediatrics of the Abia State University Teaching Hospital from January 1, 2016, to December 31, 2016, were analyzed. <strong>Results:</strong> During the study period, among the 440 overall admission, 275 children were diagnosed with malaria. The prevalence of malaria in our study was 62.5%. The male:female ratio was 1:1.2. We found, 234 (85.1%) children were &lt;5 years of age, 23 (8.2%) belonged to the age group of 5–11 years, and 18 (6.7%) were aged between &gt;11 and 16 years. The highest prevalence of malaria 40 (14.4%) occurred in September while the least 10 (3.6%) occurred in April. Around 247 (89.8%) patients were discharged home, 18 (6.5%) patients succumbed to death, and 6 (2.1%) patients were discharged against medical advice. <strong>Conclusion:</strong> The prevalence and mortality rates of malaria are high. To curb the trend of this disease, good environmental sanitation, prevention of the anophelene mosquito blood meal on humans, and early diagnosis and treatment of malaria should all be enhanced.</p> 2020-09-08T00:00:00+0530 Copyright (c) 2020 Histopathological audit of nephrectomy specimens from a single center in North India 2020-08-18T16:07:04+0530 Manishi Bansal Ankush Jindal Smriti Gupta <p><strong>Introduction:</strong> Nephrectomy is a common surgical procedure for wide variety of renal diseases, including both benign and malignant conditions. The causes of nephrectomy may vary with different geographical areas and institutions. A thorough histopathological analysis of nephrectomy specimens abets formulation of treatment guidelines specific to the geographic area. <strong>Objective:</strong> The objective of the study was to analyze trends and patterns of renal diseases requiring nephrectomy and to observe variations from the conventional pattern or geographic variation, if any. <strong>Methods:</strong> A hospital-based study was carried out to study and analyze histopathology of 38 nephrectomies done during the period of 2 years (January 2018–December 2019) at Mayo Super Specialty Hospital, Mohali, Punjab. <strong>Results:</strong> Out of 38 nephrectomies, 20 were benign and 18 were malignant. Malignant lesions were more prevalent in older age groups. Chronic pyelonephritis was most common cause of benign lesions. We observed loss of corticomedullary junction and dilatation of pelvicalyceal system in more than 80% of cases. Among malignant conditions, clear cell renal cell carcinoma was the most common histology. The World Health Organization/the International Society of Urological Pathology Grade 1 was the most common among the malignant lesions and only one case of sarcomatoid differentiation (Grade 4) was seen. <strong>Conclusion:</strong> The present study provides a detailed histopathological analysis of nephrectomies done at our institute and gives a reflection of the clinical spectrum in this part of India.</p> 2020-09-08T00:00:00+0530 Copyright (c) 2020